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英文 名稱： Anti-TNFRSF1B rabbit polyclonal antibody
別 名： p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
抗 原： TNFRSF1B
儲 存： 冷凍（-20℃）
宿 主： Rabbit
相關類別： 一抗
反應種屬： Human
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術規格
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Applications:
ELISA, WB, IHC
Name of antibody:
TNFRSF1B
Immunogen:
Fusion protein of human TNFRSF1B
Full name:
Tumor necrosis factor receptor superfamily, member 1B
Synonyms：
p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
SwissProt:
P20333
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human liver cancer and human cervical cancer
IHC Recommend dilution:
5-20
WB Predicted band size:
48 kDa
WB Positive control:
Human colon cancer
WB Recommended dilution:
200-1000
