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Background:
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9.
Applications:
ELISA, WB, IHC
Name of antibody:
RAP1B
Immunogen:
Fusion protein of human RAP1B
Full name:
Ras-related protein Rap-1b
Synonyms:
K-REV, RAL1B
SwissProt:
P61224
ELISA Recommended dilution:
1000-5000
IHC positive control:
Human thyroid cancer and human brain
IHC Recommend dilution:
50-200
WB Predicted band size:
21 kDa
WB Positive control:
HepG2 cells and Human cervical cancer tissue
WB Recommended dilution:
200-1000